Traditional Medicinals Smooth Move Senna Capsules (Pack of 50)

Traditional Medicinals Smooth Move Senna — Gentle Overnight Constipation Relief, 50 Capsules

Smooth Move is Traditional Medicinals' best-known product — an herbal senna formula that's been trusted for decades to provide predictable, overnight relief from occasional constipation. Take it before bed and it works while you sleep, typically producing a bowel movement within 6–12 hours. The capsule format offers a tasteless alternative to the original Smooth Move tea, with the same certified organic senna at the same effective dose.

How It Works

Senna (Cassia senna) leaves contain sennosides A and B — anthraquinone glycosides that function as prodrugs. After ingestion, they pass through the stomach and small intestine largely unabsorbed. In the colon, resident bacteria (including Bacteroides and Bifidobacterium species) hydrolyze the glycoside bonds and convert them to rhein anthrone — the pharmacologically active compound. Rhein anthrone works through two complementary mechanisms: it inhibits the Na+/K+-ATPase pumps in colonic epithelial cells (preventing water reabsorption from the colon, which softens stool and increases bulk), and it stimulates enteric nervous system neurons via prostaglandin release (increasing peristaltic contractions and propulsive motility). This dual secretory + motility action explains the predictable 6–12 hour window — the time needed for the sennosides to transit to the colon, undergo bacterial conversion, and take effect.

Key Features

• Sennosides A & B (Anthraquinone Glycosides): Prodrugs activated by colonic bacteria into rhein anthrone — the active compound that drives both secretory and motility effects
• Dual Mechanism: Na+/K+-ATPase inhibition (softens stool via fluid retention) + enteric nervous system stimulation (increases peristalsis) — both pathways triggered simultaneously
• Predictable 6–12 Hour Onset: Works overnight — take at bedtime, expect results by morning
• Certified USDA Organic Senna: Sustainably sourced, Non-GMO, Pharmacopoeial Grade (meets American Herbal Pharmacopoeia standards)
• Capsule Format: No herbal taste — the same effective dose as Smooth Move tea, in an easy-to-swallow pill
• 50 Capsules: Ample supply for occasional use over several months

Usage Notes

For occasional use only — not for daily long-term use. Drink plenty of water while using any senna product. Not recommended during pregnancy or for children under 12 without medical guidance.

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