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Papain — the cysteine protease enzyme found in papaya fruit — is one of the few plant-derived digestive enzymes that remains active across a wide pH range (approximately 3.5–8.0). This matters because most digestive enzymes are pH-specific: pepsin works only in the stomach's acidic environment, while pancreatic proteases function optimally in the alkaline small intestine. Papain bridges both environments, providing continuous protein-cleaving activity throughout GI transit. It cleaves peptide bonds in proteins, breaking them down into absorbable amino acids and small peptides — easing the heaviness and discomfort that follows protein-rich meals when the body's own enzyme output is insufficient. American Health's Original Papaya Enzyme pairs papain with amylase and co-enzymes for carbohydrate support in a chewable tablet format that begins working in the mouth, adding a pre-gastric enzyme phase before stomach acid. A 250-count bottle provides a generous multi-month supply at a practical price for daily use.
Chew 1–3 tablets with or immediately after meals, or as directed by your healthcare provider. Store in a cool, dry place away from moisture.
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